|   | 
Details
   web
Records
Author Kunkanjanawan, T.; Noisa, P.; Parnpai, R.
Title Modeling neurological disorders by human induced pluripotent stem cells Type Journal Article
Year 2011 Publication Journal of Biomedicine & Biotechnology Abbreviated Journal J Biomed Biotechnol
Volume (down) 2011 Issue Pages 350131
Keywords Brain/embryology/physiopathology; Cell Differentiation; Embryonic Stem Cells/*cytology; Humans; Induced Pluripotent Stem Cells/*cytology/*physiology; *Models, Neurological; Nervous System Diseases/*pathology/*physiopathology/therapy
Abstract Studies of human brain development are critical as research on neurological disorders have been progressively advanced. However, understanding the process of neurogenesis through analysis of the early embryo is complicated and limited by a number of factors, including the complexity of the embryos, availability, and ethical constrains. The emerging of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) has shed light of a new approach to study both early development and disease pathology. The cells behave as precursors of all embryonic lineages; thus, they allow tracing the history from the root to individual branches of the cell lineage tree. Systems for neural differentiation of hESCs and iPSCs have provided an experimental model that can be used to augment in vitro studies of in vivo brain development. Interestingly, iPSCs derived from patients, containing donor genetic background, have offered a breakthrough approach to study human genetics of neurodegenerative diseases. This paper summarizes the recent reports of the development of iPSCs from patients who suffer from neurological diseases and evaluates the feasibility of iPSCs as a disease model. The benefits and obstacles of iPSC technology are highlighted in order to raising the cautions of misinterpretation prior to further clinical translations.
Address Embryo Technology and Stem Cell Research Center, School of Biotechnology, Suranaree University of Technology, 111 University Avenue, Nakhon Ratchasima 30000, Thailand
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1110-7243 ISBN Medium
Area Expedition Conference
Notes PMID:22162635; PMCID:PMC3227533 Approved no
Call Number refbase @ user @ Serial 16958
Permanent link to this record
 

 
Author Abshirini, H.; Rashidi, I.; Saki, N.
Title Pathologic fractures: a neglected clinical feature of parathyroid adenoma Type Journal Article
Year 2010 Publication Case Reports in Medicine Abbreviated Journal Case Report Med
Volume (down) 2010 Issue Pages 357029
Keywords
Abstract The pattern of clinical presentation of primary hyperparathyroidism (pHPT) has changed dramatically from a severe disease to an asymptomatic condition in Western countries. The story is completely different in Eastern countries. Bone and joint related sign and symptoms like bone pain and multiple fractures are common in these patients. Imaging and nuclear medicine studies will be helpful specially in patient who candidate for surgical removal of the abnormal parathyroid gland. Here, we present a 48-year-old man with multiple typical fractures in long bones and a single adenoma in his right inferior parathyroid gland. pHPT is a severe, symptomatic disease with serious complications and high morbidity in Iran. Advanced skeletal disease is the most common pattern of presentation.
Address Otolaryngology, Head and Neck Surgery, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, P.O. Box 61537-15794, Ahvaz, Iran
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1687-9635 ISBN Medium
Area Expedition Conference
Notes PMID:21209742 Approved no
Call Number refbase @ user @ Serial 10153
Permanent link to this record
 

 
Author Abshirini, H.; Rashidi, I.; Saki, N.
Title Pathologic fractures: a neglected clinical feature of parathyroid adenoma Type Journal Article
Year 2010 Publication Case Reports in Medicine Abbreviated Journal Case Report Med
Volume (down) 2010 Issue Pages 357029
Keywords
Abstract The pattern of clinical presentation of primary hyperparathyroidism (pHPT) has changed dramatically from a severe disease to an asymptomatic condition in Western countries. The story is completely different in Eastern countries. Bone and joint related sign and symptoms like bone pain and multiple fractures are common in these patients. Imaging and nuclear medicine studies will be helpful specially in patient who candidate for surgical removal of the abnormal parathyroid gland. Here, we present a 48-year-old man with multiple typical fractures in long bones and a single adenoma in his right inferior parathyroid gland. pHPT is a severe, symptomatic disease with serious complications and high morbidity in Iran. Advanced skeletal disease is the most common pattern of presentation.
Address Otolaryngology, Head and Neck Surgery, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, P.O. Box 61537-15794, Ahvaz, Iran
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1687-9635 ISBN Medium
Area Expedition Conference
Notes PMID:21209742 Approved no
Call Number refbase @ user @ Serial 10827
Permanent link to this record
 

 
Author Ahrens, J.; Jünemann, P.
Title Transitional institutions, institutional complementarities and economic performance in China: A ‘Varieties of Capitalism’ approach Type Journal Article
Year 2010 Publication Ordnungspolitische Diskurse Abbreviated Journal
Volume (down) 2010-11 Issue Pages
Keywords institutions; China; institutional change
Abstract Zusammenfassung: The paper focuses on institutional change and institution building as integral parts of economic transition in China. China’s success, particularly compared with other advanced transition economies, implies a puzzling observation: China did not apply.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number refbase @ user @ Ahrens2010 Serial 13003
Permanent link to this record
 

 
Author Ahrens, J.; Jünemann, P.
Title Adaptive efficiency and pragmatic flexibility: characteristics of institutional change in capitalism, Chinese-style Type Journal Article
Year 2009 Publication PFH Forschungspapiere Abbreviated Journal
Volume (down) 2009 (03) Issue 03 Pages 23
Keywords institutions; China; institutional change
Abstract Since the breakdown ofthe communist world, capitalism has been considered as the unrivalled model of economy and society–a conviction deeply rooted (not only) in Western culture (Miller 2005). The late 1980s and early 1990s saw a widespread ascendancy of.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number refbase @ user @ Ahrens2009 Serial 13002
Permanent link to this record