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Author |
Smith, D.M.; Kapoor, Y.; Klinzing, G.R.; Procopio, A.T. |
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Title |
Pharmaceutical 3D printing: Design and qualification of a single step print and fill capsule |
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Journal Article |
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Year |
2018 |
Publication |
International journal of pharmaceutics |
Abbreviated Journal |
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Volume |
544 |
Issue |
1 |
Pages |
21-30 |
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Keywords |
3D printing ; Additive manufacturing ; Analysis ; Burst release ; Capsule ; Delayed release ; Fused deposition modeling ; Hot melt extrusion ; Pharmaceutical industry ; Three dimensional printing |
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Abstract |
[Display omitted] Fused deposition modeling (FDM) 3D printing (3DP) has a potential to change how we envision manufacturing in the pharmaceutical industry. A more common utilization for FDM 3DP is to build upon existing hot melt extrusion (HME) technology where the drug is dispersed in the polymer matrix. However, reliable manufacturing of drug-containing filaments remains a challenge along with the limitation of active ingredients which can sustain the processing risks involved in the HME process. To circumvent this obstacle, a single step FDM 3DP process was developed to manufacture thin-walled drug-free capsules which can be filled with dry or liquid drug product formulations. Drug release from these systems is governed by the combined dissolution of the FDM capsule shell and the dosage form encapsulated in these shells. To prepare the shells, the 3D printer files (extension .gcode) were modified by creating discrete zones, so-called zoning process, with individual print parameters. Capsules printed without the zoning process resulted in macroscopic print defects and holes. X-ray computed tomography, finite element analysis and mechanical testing were used to guide the zoning process and printing parameters in order to manufacture consistent and robust capsule shell geometries. Additionally, dose consistencies of drug containing liquid formulations were investigated in this work. |
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Elsevier B.V |
Place of Publication |
Netherlands |
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0378-5173 |
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1 @ metmet3 @ SmithDerrickM2018P3pD |
Serial  |
17807 |
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Author |
Jianchao, Z.; Zhang, T.; Faried, M.; Wengang, C. |
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Title |
3D printing cement based ink, and its application within the construction industry |
Type |
Journal Article |
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Year |
2017 |
Publication |
MATEC web of conferences |
Abbreviated Journal |
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Volume |
120 |
Issue |
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Pages |
2003 |
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Abstract |
The 3D printing technology is the engine key of the third industrial revolution, after introduction of the automation in the eighteenth century and the concept of mass production in early of twentieth century. 3D printing technology now offers the magic solution to balance both the benefits, and overcome the major associated problem with the previous concept which was the need of repetition. The 3D printing technology has two main critical success factors: the printing machine and the printing material (ink). This paper focusses on cementitious-based materials and the ability to utilize the technology in the construction industry. The research took a qualitative approach based on previous literature reviews as well as in-house research results carried out by the authors employer Research and Development Center. The paper summarizes the approach towards to an appropriate mix design which can achieve the requirement of the printing process, and overcome the current constraints which are hindering the wide application of 3D print in construction industry. The authors believe that the research topic and result will have great impact on pushing the construction industry forward towards achieving the UAE Governments strategy and target to achieve twenty-five percent (25%) of the buildings in Dubai by the year of 2030 relying on the 3D printing methodology. The research also concluded that even though the technology is adding a great value to the construction industry, it must be remembered that the technology is still in its infancy, and further research is required to achieve even higher strength printing materials that would be workable in multi-story buildings without the need of additional steel reinforcement. |
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EDP Sciences |
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2261-236x |
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1 @ metmet3 @ JianchaoZhu20173pcb |
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17806 |
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Author |
Garcia, C.R.; Rumpf, R.C.; Tsang, H.H.; Barton, J.H. |
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Title |
Effects of extreme surface roughness on 3D printed horn antenna |
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Journal Article |
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Year |
2013 |
Publication |
Electronics letters |
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Volume |
49 |
Issue |
12 |
Pages |
734-736 |
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Keywords |
Antennas ; Antennas and propagation ; Applied sciences ; Exact sciences and technology ; Radiocommunications ; Telecommunications ; Telecommunications and information theory |
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Abstract |
3D printing is an emerging technology in manufacturing. It is the long-term goal of the industry to print complex and fully functional products from cell phones to vehicles. A drawback of many 3D printing technologies is rough surface finish. It is known that metals with high surface roughness severely degrade the propagation of electromagnetic waves. Presented is the first known evaluation of the electromagnetic impact of the typical surface roughness in metal parts produced by electron beam melting. Two Ku-band (12-15 GHz) horn antennas were 3D printed, with different surface roughness, and compared to a standard horn antenna purchased from Pasternack. |
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The Institution of Engineering and Technology |
Place of Publication |
Stevenage |
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0013-5194 |
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1 @ metmet3 @ GarciaC.R2013Eoes |
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17805 |
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Author |
Gomes, J.F.B.; Wiltgen, F. |
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Title |
Avanços na manufatura aditiva em metais: técnicas, materiais e máquinas |
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Journal Article |
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Year |
2020 |
Publication |
Revista Tecnologia |
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Volume |
41 |
Issue |
1 |
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Com o advento de novas técnicas de Manufatura Aditiva foi possível à introdução de diversos metais como matéria prima e isso tem sido uma revolução para indústria, pois permite muitas possibilidades. Neste artigo serão apresentadas técnicas de impressão 3D em metais, as matérias primas metálicas mais utilizadas, os custos da manufatura aditiva comparando com a manufatura subtrativa. A utilização desta técnica na área aeronáutica e automotiva, além das dificuldades enfrentadas por esta técnica na fabricação de componentes que necessitam de grande resistência estrutural, e por fim, serão apresentadas possíveis aplicações no futuro próximo. |
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Universidade de Fortaleza |
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0101-8191 |
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Call Number |
1 @ metmet3 @ GomesJoãoFranciscoBueno2020Anma |
Serial |
17804 |
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Author |
Zucca, R.; Santos, R.C.; Lovatto, J.; Cesca, R.S.; Lovatto, F. |
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Title |
Development of a Low Cost 3D Printer Indicated to Prototyping Objects |
Type |
Journal Article |
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Year |
2019 |
Publication |
Semina. Ciências exatas e tecnológicas |
Abbreviated Journal |
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Volume |
40 |
Issue |
1 |
Pages |
47 |
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Abstract |
A indústria 4.0 vem impactando a cadeia produtiva refletindo no desenvolvimento tecnológico sustentável, sendo que o uso da impressão em 3D se encontra entre as tendências que devem criar novas oportunidades de negócios, como confecção de peças personalizadas e de difícil aquisição, entre outras. Em países como Brasil a impressora 3D comercial ainda possui elevado custo. Assim, este estudo teve por objetivo desenvolver uma impressora 3D de baixo custo, aplicando o método RepRap de auto replicação, testar, calibrar e imprimir peça para comparar com uma impressora comercial similar certificada. Realizou-se a montagem de uma impressora similar ao modelo Prusa i3 com o firmware Marlin utilizado para controle de seus componentes e software Repetier para sua configuração e controle. Como resultado foi desenvolvida a impressora 3D configurada e calibrada realizando-se a comparação de qualidade imprimindo uma peça na impressora 3D de baixo custo e em impressora comercial certificada. Também foram fabricadas peças como tela protetora e suporte para filamento, visando a melhoria do projeto. Com esta pesquisa foi possível concluir que é possível desenvolver uma impressora 3D RepRap de baixo custo se comparada à impressora comercial certificada com características idênticas quanto a precisão na qualidade final da impressão. |
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ISSN |
1676-5451 |
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Call Number |
1 @ metmet3 @ ZuccaRafael2019DoaL |
Serial |
17803 |
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