||The significant increase in natural/shale gas production in the US is causing major changes in the chemical and petrochemical markets. These changes include the increased supply of methanol and the decreased supply of propylene. As such, there are promising opportunities for methanol-to-propylene processes in the US. This paper provides a top-level techno-economic analysis of two pathways: methanol to olefins (MTO) and methanol to propylene (MTP). Base-case scenarios are simulated using ASPEN Plus to obtain the key mass and energy balances as well as design data. For each process, two scenarios are considered for the feedstock: buying methanol versus making it from natural gas. The return on investment (ROI) is calculated for both processes under broad ranges of the prices of natural gas, methanol, and products. In addition to the techno-economic analysis, the CO2 emissions are evaluated and compared.